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KMID : 0387820130200010062
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Clinical Pediatric Hematology-Oncology
2013 Volume.20 No. 1 p.62 ~ p.65
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Pneumococcal Sepsis 8 Years after Splenectomy for Chronic Immune Thrombocytopenia: A Case of Vaccinated 12-year-old Patient
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Lee Jung-Pyo
Kim Hyo-Sun
Han Jung-Woo
Lyu Chuhl-Joo
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Abstract
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Splenectomy is a safe and effective procedure in the refractory or chronic immune thrombocytopenia (ITP) patients. Overwhelming post-splenectomy infection (OPSI) is rare but fatal. The lifetime risk of post-splenectomy patients to develop an OPSI with encapsulated bacteria (Streptococcus pneumoniae, Haemophilus influenzae or Neisseria meningitidis) is about 1-5% and the mortality is reported more than 50% in 48 hours. Though vaccination against encapsulated bacteria cannot prevent all infection, vaccination is essential for the patients. We report a case of OPSI in a 12-year-old post-splenectomy boy who was vaccinated pneumococcal polysaccharide 7-valent against pneumococcus (Streptococcus pneumoniae) 2 months before splenectomy.
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KEYWORD
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Immune thrombocytopenia, Splenectomy, Pneumococcal vaccine, Sepsis
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